The Biolase GUI is a one-of-a-kind system that engages the totality of dental surgery, embodying ease of use; video education; and a highly navigable, intuitive system conducive to best medical practices. This unique GUI is minimalistic in intent, as it supports quite the sophisticated process: dental laser surgery, with 5 surgical categories integrated. Given the gravity of the surgical task, our design uses innovative human factors research as the basis for its function, considering the cognitive and emotional needs of the practitioner in an inherently challenging field.